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phosphoatm ser1981  (Cell Signaling Technology Inc)


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    Structured Review

    Cell Signaling Technology Inc phosphoatm ser1981
    Phosphoatm Ser1981, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 281 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/phosphoatm+ser1981/Phospho-ATM+(Ser1981)+Rabbit+mAb/pm41888112-515-55-57
    Average 96 stars, based on 281 article reviews
    phosphoatm ser1981 - by Bioz Stars, 2026-10
    96/100 stars

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    Related Articles

    Western Blot:

    Article Title: CHK1 is an integral regulator of DNA replication in human cells.
    Article Snippet: .. Antibodies AR TI CL E IN P RE SS The following antibodies were used for Western blotting and/or immunostaining: hemagglutinin (HA) tag (Cell Signaling Technology [CST], #2999S); phospho-RPA2 (Ser4/Ser8) (Bethyl Laboratories, A300-245A); phospho-RPA2 (Ser33) (Bethyl Laboratories, A300-246A); RPA2 (CST, #2208S); phospho-CHK1 (Ser296) (CST, #90178S); phospho-CHK1 (Ser317) (CST, #12302S); phospho-CHK1 (Ser345) (CST, #2348S); CHK1 (CST, #2360S); phosphoATM (Ser1981) (CST, #13050S); phospho-histone H2AX (Ser139; γH2AX) (CST, #9718S); histone H2AX (Bethyl Laboratories, A300-082A); phospho-histone H3 (Ser10) (Abcam, ab47297); histone H3 (Abcam, ab8898); cyclin A (Santa Cruz Biotechnology, sc-239); cyclin B (Santa Cruz Biotechnology, sc-245); FLAG tag (Sigma-Aldrich, F3165); and vinculin (SigmaAldrich, V9264). .. The CHK1 inhibitors rabusertib (LY2603618; MedChemExpress, HY-14720) and prexasertib (LY2606368; MedChemExpress, HY-18174), as well as the ATR inhibitor gartisertib (VX-803; MedChemExpress, HY-136270), were obtained from MedChemExpress.

    Article Title: cGAS/STING-mediated upregulation of NKG2D ligands in LSCs contributes to enhanced sensitivity to NK cells.
    Article Snippet: Inhibitors for PARP1/2 (Talazoparib Tosylate, Cat#: HY108413) and ATM (CGK733, Cat#: HY-15520) were purchased from MCE. .. Antibodies against PARP1 (Cat #: 66520-1-Ig, Proteintech), cGAS (Cat#: 79978, Cell signaling technology), STING (Ca#: 13647, Cell signaling technology), phospho-STING (Ser366) (Cat#:72650, Cell signaling technology), phospho-TBK1 (Ser172) (Cat#: 5483, Cell signaling technology), TBK1 (Cat#: 3504, Cell signaling technology), IRF3(Cat#: 4302, Cell signaling technology), phospho-IRF3 (Ser396) (Cat#: 4947, Cell signaling technology), ATM (Cat#: 27156-1-AP, Proteintech), phosphoATM (Ser1981) (Cat#: 5883, Cell signaling technology), phosphogH2AX (Ser139) (Cat#: 83307-2-RR, Proteintech), H2AX (Cat#: 39689, Proteintech), GAPDH (Cat#: 60004-1-Ig, Proteintech), a- Frontiers in Oncology 03 Tubulin (Cat#: 14555-1-AP, Proteintech) were used as primary antibodies in the western blotting assay; Goat Anti-Mouse IgG antibody, HRP conjugated (Cat#: 2900264, Millipore), and Goat Anti-Rabbit IgG antibody, HRP conjugated (Cat#: 3256751, Millipore) were used as second antibodies. .. Primary antibodies against human NKG2D ligands (MICA/B, ULBP1, ULBP2/5/6, and ULBP3) using in flow cytometry were purchased from R&D System, with Cat. No. as follows: FAB13001A, FAB1380A, FAB1298A, and FAB1517A, respectively; mouse anti-NKG2D antibody (Cat#: MAB139) used in functional blockade for NKG2D receptor and isotype control Goat anti-mouse IgG2AAPC (Cat#: IC003A) were obtained from R&D System.

    Immunostaining:

    Article Title: CHK1 is an integral regulator of DNA replication in human cells.
    Article Snippet: .. Antibodies AR TI CL E IN P RE SS The following antibodies were used for Western blotting and/or immunostaining: hemagglutinin (HA) tag (Cell Signaling Technology [CST], #2999S); phospho-RPA2 (Ser4/Ser8) (Bethyl Laboratories, A300-245A); phospho-RPA2 (Ser33) (Bethyl Laboratories, A300-246A); RPA2 (CST, #2208S); phospho-CHK1 (Ser296) (CST, #90178S); phospho-CHK1 (Ser317) (CST, #12302S); phospho-CHK1 (Ser345) (CST, #2348S); CHK1 (CST, #2360S); phosphoATM (Ser1981) (CST, #13050S); phospho-histone H2AX (Ser139; γH2AX) (CST, #9718S); histone H2AX (Bethyl Laboratories, A300-082A); phospho-histone H3 (Ser10) (Abcam, ab47297); histone H3 (Abcam, ab8898); cyclin A (Santa Cruz Biotechnology, sc-239); cyclin B (Santa Cruz Biotechnology, sc-245); FLAG tag (Sigma-Aldrich, F3165); and vinculin (SigmaAldrich, V9264). .. The CHK1 inhibitors rabusertib (LY2603618; MedChemExpress, HY-14720) and prexasertib (LY2606368; MedChemExpress, HY-18174), as well as the ATR inhibitor gartisertib (VX-803; MedChemExpress, HY-136270), were obtained from MedChemExpress.

    FLAG-tag:

    Article Title: CHK1 is an integral regulator of DNA replication in human cells.
    Article Snippet: .. Antibodies AR TI CL E IN P RE SS The following antibodies were used for Western blotting and/or immunostaining: hemagglutinin (HA) tag (Cell Signaling Technology [CST], #2999S); phospho-RPA2 (Ser4/Ser8) (Bethyl Laboratories, A300-245A); phospho-RPA2 (Ser33) (Bethyl Laboratories, A300-246A); RPA2 (CST, #2208S); phospho-CHK1 (Ser296) (CST, #90178S); phospho-CHK1 (Ser317) (CST, #12302S); phospho-CHK1 (Ser345) (CST, #2348S); CHK1 (CST, #2360S); phosphoATM (Ser1981) (CST, #13050S); phospho-histone H2AX (Ser139; γH2AX) (CST, #9718S); histone H2AX (Bethyl Laboratories, A300-082A); phospho-histone H3 (Ser10) (Abcam, ab47297); histone H3 (Abcam, ab8898); cyclin A (Santa Cruz Biotechnology, sc-239); cyclin B (Santa Cruz Biotechnology, sc-245); FLAG tag (Sigma-Aldrich, F3165); and vinculin (SigmaAldrich, V9264). .. The CHK1 inhibitors rabusertib (LY2603618; MedChemExpress, HY-14720) and prexasertib (LY2606368; MedChemExpress, HY-18174), as well as the ATR inhibitor gartisertib (VX-803; MedChemExpress, HY-136270), were obtained from MedChemExpress.

    other:

    Article Title: Genistein Enhances Radiosensitivity of Human Hepatocellular Carcinoma Cells by Inducing G2/M Arrest and Apoptosis
    Article Snippet: a Department of Food Science and Engineering, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai 200240, China; b Department of Laboratory Medicine, Changhai Hospital, Second Military Medical University, Shanghai, China; c Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, Shanghai, China; d Department of Pathology, Shanghai East Hospital, Tongji University, Shanghai, China; and e Department of Surgery, Penglai People’s Hospital, Penglai 265600, Shandong Province, China

    Article Title: Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells.
    Article Snippet: Cucurbitacin B (Cuc B), a natural compound extracted from cucurbitaceous plants, demonstrated potent anticancer activities, while the underlying mechanisms remain unclear.. We investigated the anticancer effect of Cuc B on MCF-7 breast cancer cells.. Cuc B drastically decreased cell viability in a concentration-dependent manner.



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